Yazar "Çalışkan, Tezcan" için listeleme
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Are Intervertebral Disc Tissue Cells Damaged When Attempting to Prevent Thrombus Formation Using Dabigatran, A New Oral Anticoagulant?
Kaplan, Necati; Karaarslan, Numan; Yılmaz, İbrahim; Yasar Şirin, Duygu; Akgün, Feride Sinem; Çalışkan, Tezcan; Özbek, Hanefi (Turkish Neurosurgical Soc, 2019)AIM: To investigate the effect of dabigatran, a new oral anticoagulant, on human primary cell cultures isolated from intact intervertebral disc tissue. MATERIAL and METHODS: Cell cultures were prepared from tissues obtained ... -
Are radio-contrast agents commonly used in discography toxic to the intact intervertebral disc tissue cells?
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Şirin, Duygu Yaşar; Kaplan, Necati; Çalışkan, Tezcan; Ateş, Özkan (Wiley, 2019)In the literature, there have been no studies showing clear results on how radio-contrast pharmaceuticals would affect intact disc tissue cells. In this context, it was aimed to evaluate the effects of iopromide and gadoxetic ... -
Beyin Tümörü Olgularında İntraoperatif Ultrasonografi Kullanımının Rezeksiyon Oranına Etkisi
Tunçkale, Tamer; Çalışkan, Tezcan (2021)Amaç: İntraoperatif ultrasonografi eş zamanlı görüntü sağlayan, kolay erişilebilen, minimum riskli ve uygun maliyetli bir görüntüleme tekniğidir. Bu özelliklerine rağmen halen yaygın kullanılmamaktadır. Bu araştırmada ... -
Comparison of the Surgical Results for Foramen Magnum Decompression with and without Duraplasty in Chiari Malformation Type 1
Gürbüz, Mehmet Sabri; Karaarslan, Numan; Çalışkan, Tezcan; Ünal, Emre; Berkman, Mehmet Zafer (Turkish Neurosurgical Soc, 2015)AIM: The surgical results for foramen magnum decompression (FMD) with and without duraplasty in Chiari Malformation type 1 (CM-1) were compared retrospectively. MATERIAL and METHODS: Thirty-nine cases of CM-1 with and ... -
Diklofenak Sodyum ve Montelukast Sodyumun Travmatik Omurilik Yaralanmalarında Akut Enflamasyon Üzerindeki Koruyucu Etkileri: Sıçanlarda Deneysel Bir Çalışma
İş, Merih; Aker, Fügen; Ceman, Duygu; Erdoğan, Barış; Engin, Taner; Tunçkale, Tamer; Çalışkan, Tezcan (2022)Amaç: Bu çalışmanın amacı travmatik omurilik yaralanmasında (T-SCI) diklofenak sodyum (DF) ve montelukast sodyumun (ML) akut enflamasyon üzerindeki koruyucu etkilerini araştırmaktır. Gereç ve Yöntem: Kırk Sprague-Dawley ... -
Effect of Antithrombotic Therapy on Development of Acute Subdural Hematoma After Burr Hole Drainage of Chronic Subdural Hematoma
Yüksel, Mehmet Onur; Çevik, Serdar; Erdoğan, Barış; Tunçkale, Tamer; Katar, Salim; Işık, Semra; Evran, Şevket; Çalışkan, Tezcan (Turkish Neurosurgical Soc, 2020)AIM: To evaluate the relationship between the time from cessation of anticoagulant/antiplatelet medication to surgery and risk of postoperative acute subdural hematoma (ASDH) after burr hole drainage of chronic subdural ... -
The Effect of Matrix Metalloproteinase-3 on the Prognosis and Biological Behaviour of Meningiomas
Karaarslan, Numan; Gürbüz, Mehmet Sabri; Çalışkan, Tezcan; Ayan, Erdoğan; Vardar Aker, Fugen; Berkman, Mehmet Zafer (Turkish Neurosurgical Soc, 2016)AIM: To analyse the effect of MMP-3 (Matrix Metalloproteinase Enzyme-3)-one of the extracellular matrix proteins-on the prognosis and biological behaviour of meningiomas. MATERIAL and METHODS: 79 cases of meningioma that ... -
Effect of naproxen on proliferation and differentiation of primary cell cultures isolated from human cartilage tissue
Karaarslan, Numan; Batmaz, Ahmet Güray; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Şirin, Duygu Yaşar; Ateş, Özkan (Spandidos Publ Ltd, 2018)Non-steroidal anti-inflammatory drugs (NSAIDs) that are applied through oral, injectable or topical routes have been widely used in painful and inflammatory musculoskeletal diseases. The current study aimed to determine ... -
The Effectiveness of the Amount of Polymethylmethacrylate Used in the Treatment of Lumbar Osteoporotic Compression Fractures
Yüksel, Mehmet Onur; Çevik, Serdar; Erdoğan, Barış; Katar, Salim; Tunçkale, Tamer; Çalışkan, Tezcan; Evran, Şevket (Yerkure Tanitim & Yayincilik Hizmetleri A S, 2020)Objective: We aimed to investigate the effectiveness of the amount of polymethylmethacrylate used in pain control and maintenance of long-term vertebra corpus height in patients undergoing percutaneous vertebroplasty due ... -
Effects of etanercept, a tumor necrosis factor receptor fusion protein, on primary cell cultures prepared from intact human intervertebral disc tissue
Çalışkan, Tezcan; Şirin, Duygu Yaşar; Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Akyuva, Yener; Ateş, Özkan; Şimşek, Abdullah Talha (Spandidos Publ Ltd, 2019)The aim of the present study was to investigate the effects of etanercept (ETA), a tumor necrosis factor (TNF) inhibitor, on human cell cultures prepared from intact intervertebral disc tissue. ETA is used as a treatment ... -
The Effects of NLR on the Diagnosis and Pharmacological Management of Brain Abscesses
Çalışkan, Tezcan; Yılmaz, İbrahim; Hacıoğlu Kasım, Fatma Bahar; Ersöz, Emel; Doğan, Mustafa; Karaarslan, Numan (2021)Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, ... -
The effects of rivaroxaban, an oral anticoagulant, on human IVD primary cultures
Çalışkan, Tezcan; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Şirin, Duygu Yaşar; Özbek, Hanefi (Termedia Publishing House Ltd, 2022)Introduction: The present study aimed to investigate the potential effects of rivaroxaban, an oral anticoagulant that inhibits the effects of factor Xa, on intact intervertebral disc tissue cells and the extracellular ... -
The Effects of Sodium Fluorescein Dyeing of Metastatic Brain Tumors on Surgical Outcomes Under Microsurgical Operation
Tunçkale, Tamer; Çalışkan, Tezcan (2021)Aim: We investigated the reflection of tumor dyeing (staining), an auxiliary technique for the resection of metastases, which are the most prevalentgroup among brain tumors, via microsurgery.Materials and Methods: Twenty ... -
Evaluation of neutrophil-to-lymphocyte ratio as a marker of inflammatory response in spondylodiscitis
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalışkan, Tezcan; Doğan, Mustafa; Bilir, Bülent; Ateş, Özkan (2018)Aim: Spondylodiscitis, if not diagnosed on time, can cause morbidity or mortality at high rates. This study was carried out with the aim of testing the hypothesis that “neutrophil-to-lymphocyte ratio can be used” especially ... -
Evaluation of the Effect of Daptomycin, a Glycopeptide Agent, on Intact Intervertebral Disc Tissue
Kaplan, Necati; Yılmaz, İbrahim; Karaarslan, Numan; Yasar Şirin, Duygu; Şimşek, Abdullah Talha; Çalışkan, Tezcan; Özbek, Hanefi (Turkish Neurosurgical Soc, 2019)AIM: To evaluate the effects of pre- and intra-operatively administered daptomycin (DAP) on the intact human primary intervertebral disc tissue cells. MATERIAL and METHODS: Primary cell cultures were established using ... -
Factors Affecting on the Prognosis in Multiple Intracranial Aneurysms
Background: With improvements in diagnostic methods, the incidence of multiple intracranial aneurysms has increased up to35%. Factors influential on outcome in multiple intracranial aneurysms are still debatable. We aimed ... -
The Impact of Various Breast Sizes of Women on Vertebral Column and Spinopelvic Parameters
Tunçkale, Tamer; Gürdal, Sibel Özkan; Çalışkan, Tezcan; Topçu, Birol; Yüksel, Mehmet Onur (Turkish Neurosurgical Society, 2021)AIM: To find out the anatomical changes in spine and pelvis, and the impact of various breast sizes of women on the quality of life. MATERIAL and METHODS: Sixty women with back pain volunteered to participate in this study. ... -
Intraabdominal Pseudocyst Developed after Ventriculoperitoneal Shunt: A Case Report
Ayan, Erdoğan; Tanriverdi, Halil İbrahim; Çalışkan, Tezcan; Senel, Ufuk; Karaarslan, Numan (Premchand Shantidevi Research Foundation, 2015)Abdominal pseudocyst is a rare complication developing after ventriculoperitoneal shunt treatment. It is more commonly seen particularly in children. The underlying pathogenesis may be associated with repeat revisions or ... -
Investigation of serum E-Cadherin, VEGF121, Survivin, Tenascin C and Tetraspanin 8 levels in patients with glioblastoma
Tunçkale, Tamer; Çalışkan, Tezcan; Potoğlu, Bilgehan; Engin, Taner; Güzel, Savaş; Çelikkol, Aliye; Yılmaz, Ahsen (Aepress Sro, 2023)OBJECTIVE: The aim of this study is to determine biomarkers, which may be used in order to understand the pathophysiology, the diagnosis, progression surveillance/monitoring, and treatment efficacy of high graded glial ... -
Investigation of the effect of dipyrone on cells isolated from intervertebral disc tissue
Akgün, Feride Sinem; Şirin, Duygu Yaşar; Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi; Şimşek, Abdullah Talha; Ateş, Özkan; Çalışkan, Tezcan (Spandidos Publ Ltd, 2019)The present study aimed to evaluate the effects of dipyrone, an indispensable analgesic, anti-pyretic and anti-spasmodic used in emergency departments, on nucleus pulposus and annulus fibrosus cells in vitro. After surgical ...